https://www.stephanecastel.com/home daily 1.0 2025-12-01 https://images.squarespace-cdn.com/content/v1/5e9caa3d70b35e438cf52d3e/1587923454923-QQH08YPCK3O0NYKYW676/Cocktail-63-crop.png Stephane Castel - Hi. I’m a Computational Geneticist and Entrepreneur who is passionate about using cutting-edge science to positively impact global health. I received my PhD from Cold Spring Harbor Laboratory and did post-doctoral training at Columbia University. My academic research has focused on the role of non-coding genetic variation in disease. I have co-founded two companies, Fiix and Variant Bio. https://images.squarespace-cdn.com/content/v1/5e9caa3d70b35e438cf52d3e/5f1fb82b-9cd2-4258-b25d-0508404b6518/Screenshot+2025-01-07+at+9.04.50%E2%80%AFAM.png Stephane Castel https://images.squarespace-cdn.com/content/v1/5e9caa3d70b35e438cf52d3e/e28cf80b-4952-40bf-940f-b0511a6041b0/Screenshot+2025-01-07+at+9.05.17%E2%80%AFAM.png Stephane Castel https://images.squarespace-cdn.com/content/v1/5e9caa3d70b35e438cf52d3e/1587343415355-WNST2GY49D58WCBNUT99/Screen+Shot+2020-04-19+at+5.42.47+PM.png Stephane Castel - The Genotype Tissue Expression Project The Genotype Tissue Expression (GTEx) project aims to understand the effect of genetic variation on gene expression across diverse human tissues, and is one of the largest eQTL studies to date. As a lead analyst in the GTEx Analysis Working Group I have contributed to studies of cis and trans regulatory effects, and am responsible for the generation and analysis of allele-specific expression data. https://images.squarespace-cdn.com/content/v1/5e9caa3d70b35e438cf52d3e/1587336818738-5FDL36NO5BFNNYTHY5HC/Screen+Shot+2020-04-19+at+3.53.21+PM.png Stephane Castel - Tools for Functional Genomics I have developed numerous tools for integrating genomic and transcriptomic data, particularly in the context of expression quantitative trait loci (eQTL) and allele-specific expression (ASE) analyses.